RHONDA PERCIAVALLE PATRICK, PH.D - HOW TO PERSONALIZE YOUR NUTRITION BASED ON YOUR GENES

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SNP rsID Minor Allele RefSNP Alleles
APOE   rs429358 C C/T
BCMO1   rs12934922 T A/T
BCMO1   rs7501331 T C/T
CYP2R1   rs10741657 A A/G
CYP2R1   rs12794714 A A/G
CYP2R1   rs2060793 A A/G
FADS1   rs174548 G C/G
FADS2   rs1535 G A/G
FOXO3   rs2802292 G G/T
FUT2   rs492602 G C/T
FUT2   rs602662 A A/G
MTHFR C677T   rs1801133 A C/T
MYRF   rs174537 T G/T
NBPF3   rs4654748 T C/T
PEMT   rs12325817 G C/G
PEMT   rs7946 T C/T
Richard Lewis
Richard Lewis  

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SNPs mentioned in Dr Rhonda Patrick's nutrigenomics PDF report, available here: http://www.foundmyfitness.com/?sendme=nutrigenomics
(N.B. I am not affiliated. Referenced without consent. )


Genes in this template

Official name:

The official name of this gene is "cytochrome P450, family 2, subfamily R, polypeptide 1." CYP2R1 is the gene's official symbol. The CYP2R1 gene is also known by other names, listed below. Read more about gene names and symbols on the About page.

Normal function:

From NCBI Gene : This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ...



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Genome Wide Studies
  • Study on rs429358 - Alzheimer's disease biomarkers. 

    Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.

    Population: None )

    Pubmed reference: 21123754


  • Study on rs10741657 - Vitamin D insufficiency. 

    Common genetic determinants of vitamin D insufficiency: a genome-wide association study.

    Population: 17,871 European ancestry individuals ( Replicated in another study with 17,871 European ancestry individuals )

    Pubmed reference: 20541252


  • Study on rs2060793 rs1993116 - Vitamin D levels.  Reduced Risk in people with AA genotype ( Odds Ratio: 0.25 ).

    Genome-wide association study of circulating vitamin D levels.

    Population: 2,221 European ancestry individuals ( Replicated in another study with 2,221 European ancestry individuals )

    Pubmed reference: 20418485


  • Study on rs174548 - Metabolite levels. 

    Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum.

    Population: None )

    Pubmed reference: 19043545


  • Study on rs1535 - Metabolic syndrome.  Reduced Risk in people with GG genotype ( Odds Ratio: 0.03 ).

    A genome-wide association study of the metabolic syndrome in Indian Asian men.

    Population: 2,240 Indian Asian ancestry individuals ( Replicated in another study with 2,240 Indian Asian ancestry individuals )

    Pubmed reference: 20694148


  • Study on rs492602 - Vitamin B12 levels.  Reduced Risk in people with GG genotype ( Odds Ratio: 0.09 ).

    Common variants of FUT2 are associated with plasma vitamin B12 levels.

    Population: 1,059 European ancestry female individuals ( Replicated in another study with 1,059 European ancestry female individuals )

    Pubmed reference: 18776911


  • Study on rs602662 - Folate pathway vitamin levels. 

    Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.

    Population: None )

    Pubmed reference: 19744961


  • Study on rs1801133 - Homocysteine levels.  Reduced Risk in people with AA genotype ( Odds Ratio: 0.16 ).

    Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.

    Population: None )

    Pubmed reference: 23824729


  • Study on rs174537 rs4246215 rs174550 rs1535 - Colorectal cancer.  Increased Risk in people with GG genotype ( Odds Ratio: 1.16 ).

    Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.

    Population: 12,865 East Asian ancestry cases, 25,773 East Asian ancestry controls, up to 16,984 European ancestry cases, up to 18,262 European ancestry controls ( Replicated in another study with 12,865 East Asian ancestry cases, 25,773 East Asian ancestry controls, up to 16,984 European ancestry cases, up to 18,262 European ancestry controls )

    Pubmed reference: 24836286


  • Study on rs4654748 - Folate pathway vitamin levels.  Increased Risk in people with CC genotype ( Odds Ratio: 1.45 ).

    Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations.

    Population: 686 European ancestry individuals ( Replicated in another study with 686 European ancestry individuals )

    Pubmed reference: 19303062