Omega-3 fatty acids (fish oil):
Omega-3 fatty acids (fish oil): as it relates to Chronic Pain in Health report: COMT and Chronic Pain Susceptibility
Reduction of Inflammation:
Omega-3 fatty acids have anti-inflammatory properties that can help reduce inflammation in the body. Chronic pain is often associated with inflammation, so incorporating fish oil into your diet may help alleviate some of the pain.Improved Joint Health:
Omega-3 fatty acids have been found to support joint health by reducing stiffness and improving mobility. This can be particularly beneficial for individuals suffering from chronic pain conditions such as arthritis.Enhanced Nerve Function:
Omega-3 fatty acids play a crucial role in maintaining healthy nerve function. By supporting nerve health, fish oil can help reduce nerve-related pain and discomfort associated with conditions like neuropathy.Regulation of Pain Perception:
Some studies suggest that omega-3 fatty acids may help regulate pain perception in the brain, potentially reducing the intensity of chronic pain symptoms. Incorporating fish oil supplements or increasing your intake of omega-3 rich foods such as salmon, mackerel, and walnuts may be beneficial for managing chronic pain. However, it's important to consult with a healthcare provider before starting any new supplement regimen, especially if you are taking medications or have underlying health conditions.Supplements for Chronic Pain
Here are some dietary supplements related to the content in this report. Click the shopping cart to purchase the supplement from our partners.
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Curcumin (turmeric)
Shown to inhibit COMT activity and increase dopamine levels in the brain. Also has anti-inflammatory effects.
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Omega-3 fatty acids (fish oil):
May reduce inflammation that contributes to pain. Also may protect neurons that use dopamine.
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Magnesium
Required for COMT enzymatic reactions. Supplements may help for those deficient.
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Rhodiola rosea
Herb that may inhibit COMT, especially in the Met/Met genotype. May prolong dopamine effects.
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SAM-e
Supplement that provides methyl groups needed for COMT methylation reactions. May support COMT function.
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Devil's claw
Natural anti-inflammatory that may reduce inflammatory pain. Also thought to interact with neurotransmitter systems.
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Cayenne/Capsaicin
Compound found in hot chili peppers that depletes substance P, a neurotransmitter involved in pain signaling.
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Valerian root
Herbal anxiolytic that may increase GABA, a neurotransmitter associated with reduced pain perception.
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St. John's Wort
Herb that may inhibit COMT activity similar to some pain medications. Also boosts serotonin which improves mood.
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Peppermint oil
Menthol is a COMT inhibitor. Peppermint oil applied topically may enhance painkilling dopamine effects.
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Boswellia
Anti-inflammatory herb that may disrupt cytokine signaling implicated in pain hypersensitivity.
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Cannabidiol (CBD)
Compound from cannabis that affects endocannabinoid receptors involved in pain processing.
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DLPA
Supplement containing amino acids that may prevent breakdown of endorphins for natural pain relief.
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5-HTP
Supplement that increases serotonin levels which may help with fibromyalgia and comorbid depression.
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Ginger
Contains anti-inflammatory gingerols that may inhibit pain-causing prostaglandins and leukotrienes.
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Arnica
Homeopathic pain remedy used topically that may reduce inflammation and impact serotonin.
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