Rhodiola rosea

Rhodiola rosea as it relates to Chronic Pain in Health report: COMT and Chronic Pain Susceptibility

Rhodiola rosea, also known as golden root or arctic root, is an adaptogenic herb that has been traditionally used to help the body adapt to stress and improve physical and mental performance. In the context of chronic pain, Rhodiola rosea may offer some benefits due to its anti-inflammatory and analgesic properties.

Anti-inflammatory properties:

Rhodiola rosea contains active compounds such as salidroside and rosavin, which have been shown to have anti-inflammatory effects. Chronic pain is often associated with inflammation in the body, so the anti-inflammatory properties of Rhodiola rosea may help reduce pain and discomfort.

Analgesic properties:

Studies have suggested that Rhodiola rosea may have analgesic effects, meaning it can help reduce pain perception. This can be particularly beneficial for individuals suffering from chronic pain conditions such as arthritis, fibromyalgia, or lower back pain.

Stress reduction:

Chronic pain is often linked to stress and anxiety, which can exacerbate pain symptoms. Rhodiola rosea is known for its ability to help the body cope with stress and improve mood, which may indirectly help in managing chronic pain.

Improving energy and endurance:

Chronic pain can be draining both physically and mentally. Rhodiola rosea is believed to enhance energy levels and endurance, which can be beneficial for individuals dealing with chronic pain who may experience fatigue and reduced physical activity.

Overall, while more research is needed to fully understand the effects of Rhodiola rosea on chronic pain, its anti-inflammatory, analgesic, stress-reducing, and energy-boosting properties make it a promising natural supplement for individuals looking for alternative ways to manage their chronic pain.

Supplements for Chronic Pain

Here are some dietary supplements related to the content in this report. Click the shopping cart to purchase the supplement from our partners.

  1. Curcumin (turmeric)

    Shown to inhibit COMT activity and increase dopamine levels in the brain. Also has anti-inflammatory effects.

  2. Omega-3 fatty acids (fish oil):

    May reduce inflammation that contributes to pain. Also may protect neurons that use dopamine.

  3. Magnesium

    Required for COMT enzymatic reactions. Supplements may help for those deficient.

  4. Rhodiola rosea

    Herb that may inhibit COMT, especially in the Met/Met genotype. May prolong dopamine effects.

  5. SAM-e

    Supplement that provides methyl groups needed for COMT methylation reactions. May support COMT function.

  6. Devil's claw

    Natural anti-inflammatory that may reduce inflammatory pain. Also thought to interact with neurotransmitter systems.

  7. Cayenne/Capsaicin

    Compound found in hot chili peppers that depletes substance P, a neurotransmitter involved in pain signaling.

  8. Valerian root

    Herbal anxiolytic that may increase GABA, a neurotransmitter associated with reduced pain perception.

  9. St. John's Wort

    Herb that may inhibit COMT activity similar to some pain medications. Also boosts serotonin which improves mood.

  10. Peppermint oil

    Menthol is a COMT inhibitor. Peppermint oil applied topically may enhance painkilling dopamine effects.

  11. Boswellia

    Anti-inflammatory herb that may disrupt cytokine signaling implicated in pain hypersensitivity.

  12. Cannabidiol (CBD)

    Compound from cannabis that affects endocannabinoid receptors involved in pain processing.

  13. DLPA

    Supplement containing amino acids that may prevent breakdown of endorphins for natural pain relief.

  14. 5-HTP

    Supplement that increases serotonin levels which may help with fibromyalgia and comorbid depression.

  15. Ginger

    Contains anti-inflammatory gingerols that may inhibit pain-causing prostaglandins and leukotrienes.

  16. Arnica

    Homeopathic pain remedy used topically that may reduce inflammation and impact serotonin.

It is essential to consult your healthcare provider before starting any of these supplements. They can have side effects, and some may interact with medications or other supplements you're already taking.
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