Rhodiola rosea

Rhodiola rosea as it relates to Chronic Pain in Health report: COMT and Chronic Pain Susceptibility

Rhodiola rosea, also known as golden root or arctic root, is an adaptogenic herb that has been traditionally used to help the body adapt to stress and improve physical and mental performance. In the context of chronic pain, Rhodiola rosea may offer some benefits due to its anti-inflammatory and analgesic properties.

Anti-inflammatory properties

Rhodiola rosea has been shown to have anti-inflammatory effects, which can help reduce inflammation in the body that may be contributing to chronic pain. By decreasing inflammation, Rhodiola rosea may help alleviate pain and improve overall comfort.

Analgesic properties

Studies have suggested that Rhodiola rosea may have analgesic properties, meaning it can help reduce pain perception. This can be particularly beneficial for individuals suffering from chronic pain conditions, as it may help manage their symptoms and improve their quality of life.

Stress reduction

Chronic pain is often associated with increased stress levels, which can exacerbate pain symptoms. Rhodiola rosea is known for its ability to help the body cope with stress and promote a sense of calm and relaxation. By reducing stress levels, Rhodiola rosea may indirectly help alleviate chronic pain. Overall, Rhodiola rosea may be a beneficial supplement for individuals dealing with chronic pain, as it can help reduce inflammation, alleviate pain, and promote stress reduction. However, it is important to consult with a healthcare provider before incorporating Rhodiola rosea into your pain management regimen to ensure it is safe and appropriate for your individual needs.

Supplements for Chronic Pain

Here are some dietary supplements related to the content in this report. Click the shopping cart to purchase the supplement from our partners.

  1. Curcumin (turmeric)

    Shown to inhibit COMT activity and increase dopamine levels in the brain. Also has anti-inflammatory effects.

  2. Omega-3 fatty acids (fish oil):

    May reduce inflammation that contributes to pain. Also may protect neurons that use dopamine.

  3. Magnesium

    Required for COMT enzymatic reactions. Supplements may help for those deficient.

  4. Rhodiola rosea

    Herb that may inhibit COMT, especially in the Met/Met genotype. May prolong dopamine effects.

  5. SAM-e

    Supplement that provides methyl groups needed for COMT methylation reactions. May support COMT function.

  6. Devil's claw

    Natural anti-inflammatory that may reduce inflammatory pain. Also thought to interact with neurotransmitter systems.

  7. Cayenne/Capsaicin

    Compound found in hot chili peppers that depletes substance P, a neurotransmitter involved in pain signaling.

  8. Valerian root

    Herbal anxiolytic that may increase GABA, a neurotransmitter associated with reduced pain perception.

  9. St. John's Wort

    Herb that may inhibit COMT activity similar to some pain medications. Also boosts serotonin which improves mood.

  10. Peppermint oil

    Menthol is a COMT inhibitor. Peppermint oil applied topically may enhance painkilling dopamine effects.

  11. Boswellia

    Anti-inflammatory herb that may disrupt cytokine signaling implicated in pain hypersensitivity.

  12. Cannabidiol (CBD)

    Compound from cannabis that affects endocannabinoid receptors involved in pain processing.

  13. DLPA

    Supplement containing amino acids that may prevent breakdown of endorphins for natural pain relief.

  14. 5-HTP

    Supplement that increases serotonin levels which may help with fibromyalgia and comorbid depression.

  15. Ginger

    Contains anti-inflammatory gingerols that may inhibit pain-causing prostaglandins and leukotrienes.

  16. Arnica

    Homeopathic pain remedy used topically that may reduce inflammation and impact serotonin.

It is essential to consult your healthcare provider before starting any of these supplements. They can have side effects, and some may interact with medications or other supplements you're already taking.
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