Rhodiola rosea
Rhodiola rosea as it relates to Chronic Pain in Health report: COMT and Chronic Pain Susceptibility
Benefits for Chronic Pain:
Rhodiola rosea has also shown promise in managing chronic pain conditions. Some studies suggest that its anti-inflammatory and analgesic properties may help reduce pain levels in individuals suffering from conditions such as fibromyalgia, arthritis, or lower back pain.
Mechanism of Action:
The exact mechanism by which Rhodiola rosea alleviates chronic pain is not fully understood. However, it is believed that its ability to modulate the body's stress response and reduce inflammation may play a role in its pain-relieving effects.
Usage:
Rhodiola rosea can be consumed in various forms, including capsules, extracts, teas, or tinctures. It is important to consult with a healthcare provider before using Rhodiola rosea, especially if you are taking medications or have underlying health conditions.
Conclusion:
While more research is needed to fully understand the effects of Rhodiola rosea on chronic pain, preliminary studies suggest that it may offer a natural and potentially effective option for managing pain and improving quality of life for individuals with chronic pain conditions.
Supplements for Chronic Pain
Here are some dietary supplements related to the content in this report. Click the shopping cart to purchase the supplement from our partners.
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Curcumin (turmeric)
Shown to inhibit COMT activity and increase dopamine levels in the brain. Also has anti-inflammatory effects.
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Omega-3 fatty acids (fish oil):
May reduce inflammation that contributes to pain. Also may protect neurons that use dopamine.
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Magnesium
Required for COMT enzymatic reactions. Supplements may help for those deficient.
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Rhodiola rosea
Herb that may inhibit COMT, especially in the Met/Met genotype. May prolong dopamine effects.
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SAM-e
Supplement that provides methyl groups needed for COMT methylation reactions. May support COMT function.
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Devil's claw
Natural anti-inflammatory that may reduce inflammatory pain. Also thought to interact with neurotransmitter systems.
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Cayenne/Capsaicin
Compound found in hot chili peppers that depletes substance P, a neurotransmitter involved in pain signaling.
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Valerian root
Herbal anxiolytic that may increase GABA, a neurotransmitter associated with reduced pain perception.
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St. John's Wort
Herb that may inhibit COMT activity similar to some pain medications. Also boosts serotonin which improves mood.
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Peppermint oil
Menthol is a COMT inhibitor. Peppermint oil applied topically may enhance painkilling dopamine effects.
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Boswellia
Anti-inflammatory herb that may disrupt cytokine signaling implicated in pain hypersensitivity.
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Cannabidiol (CBD)
Compound from cannabis that affects endocannabinoid receptors involved in pain processing.
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DLPA
Supplement containing amino acids that may prevent breakdown of endorphins for natural pain relief.
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5-HTP
Supplement that increases serotonin levels which may help with fibromyalgia and comorbid depression.
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Ginger
Contains anti-inflammatory gingerols that may inhibit pain-causing prostaglandins and leukotrienes.
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Arnica
Homeopathic pain remedy used topically that may reduce inflammation and impact serotonin.
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