Valerian root

Valerian root as it relates to Chronic Pain in Health report: COMT and Chronic Pain Susceptibility

Valerian root is a popular herbal remedy that has been used for centuries to help with various health issues, including chronic pain.

Benefits of Valerian Root for Chronic Pain:

  • Pain Relief: Valerian root has natural sedative and anti-inflammatory properties that can help reduce pain and discomfort associated with chronic conditions such as arthritis, fibromyalgia, and migraines.
  • Relaxation: Valerian root is known for its calming effects on the nervous system, which can help alleviate stress and tension that often exacerbate chronic pain.
  • Improved Sleep: Chronic pain can disrupt sleep patterns, leading to fatigue and increased pain sensitivity. Valerian root can help promote better sleep quality, allowing the body to heal and recover more effectively.

How to Use Valerian Root for Chronic Pain:

Valerian root is commonly available in various forms, including capsules, tinctures, and teas. It is recommended to consult with a healthcare provider or a qualified herbalist before using valerian root for chronic pain, especially if you are taking any medications or have underlying health conditions.

Typical dosages for valerian root range from 300-900 mg per day, depending on the severity of the pain and individual tolerance levels. It is best to start with a lower dose and gradually increase as needed.

Precautions:

While valerian root is generally considered safe for most people, some individuals may experience side effects such as dizziness, drowsiness, or digestive issues. It is not recommended for pregnant or breastfeeding women, children, or individuals with liver disease.

It is important to use valerian root as directed and to discontinue use if you experience any adverse reactions. If you are unsure about using valerian root for chronic pain, it is best to seek guidance from a healthcare professional.

Supplements for Chronic Pain

Here are some dietary supplements related to the content in this report. Click the shopping cart to purchase the supplement from our partners.

  1. Curcumin (turmeric)

    Shown to inhibit COMT activity and increase dopamine levels in the brain. Also has anti-inflammatory effects.

  2. Omega-3 fatty acids (fish oil):

    May reduce inflammation that contributes to pain. Also may protect neurons that use dopamine.

  3. Magnesium

    Required for COMT enzymatic reactions. Supplements may help for those deficient.

  4. Rhodiola rosea

    Herb that may inhibit COMT, especially in the Met/Met genotype. May prolong dopamine effects.

  5. SAM-e

    Supplement that provides methyl groups needed for COMT methylation reactions. May support COMT function.

  6. Devil's claw

    Natural anti-inflammatory that may reduce inflammatory pain. Also thought to interact with neurotransmitter systems.

  7. Cayenne/Capsaicin

    Compound found in hot chili peppers that depletes substance P, a neurotransmitter involved in pain signaling.

  8. Valerian root

    Herbal anxiolytic that may increase GABA, a neurotransmitter associated with reduced pain perception.

  9. St. John's Wort

    Herb that may inhibit COMT activity similar to some pain medications. Also boosts serotonin which improves mood.

  10. Peppermint oil

    Menthol is a COMT inhibitor. Peppermint oil applied topically may enhance painkilling dopamine effects.

  11. Boswellia

    Anti-inflammatory herb that may disrupt cytokine signaling implicated in pain hypersensitivity.

  12. Cannabidiol (CBD)

    Compound from cannabis that affects endocannabinoid receptors involved in pain processing.

  13. DLPA

    Supplement containing amino acids that may prevent breakdown of endorphins for natural pain relief.

  14. 5-HTP

    Supplement that increases serotonin levels which may help with fibromyalgia and comorbid depression.

  15. Ginger

    Contains anti-inflammatory gingerols that may inhibit pain-causing prostaglandins and leukotrienes.

  16. Arnica

    Homeopathic pain remedy used topically that may reduce inflammation and impact serotonin.

It is essential to consult your healthcare provider before starting any of these supplements. They can have side effects, and some may interact with medications or other supplements you're already taking.
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