Valerian root
Valerian root as it relates to Chronic Pain in Health report: COMT and Chronic Pain Susceptibility
Valerian Root for Chronic Pain
Valerian root is a natural herb that has been used for centuries to help with various health issues, including chronic pain. It is believed to have sedative and anti-inflammatory properties that can help alleviate pain and promote relaxation.
Chronic pain is a persistent condition that can be debilitating and affect a person's quality of life. Many people turn to natural remedies like valerian root to help manage their pain without the side effects of prescription medications.
Valerian root can be taken in various forms, including as a tea, tincture, or supplement. It is often used to help with conditions such as arthritis, fibromyalgia, and migraines, which are common causes of chronic pain.
While more research is needed to fully understand the effects of valerian root on chronic pain, many people report positive results from using this herb as part of their pain management regimen. It is always important to consult with a healthcare provider before starting any new treatment, especially if you are already taking medications for chronic pain.
Supplements for Chronic Pain
Here are some dietary supplements related to the content in this report. Click the shopping cart to purchase the supplement from our partners.
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Curcumin (turmeric)
Shown to inhibit COMT activity and increase dopamine levels in the brain. Also has anti-inflammatory effects.
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Omega-3 fatty acids (fish oil):
May reduce inflammation that contributes to pain. Also may protect neurons that use dopamine.
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Magnesium
Required for COMT enzymatic reactions. Supplements may help for those deficient.
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Rhodiola rosea
Herb that may inhibit COMT, especially in the Met/Met genotype. May prolong dopamine effects.
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SAM-e
Supplement that provides methyl groups needed for COMT methylation reactions. May support COMT function.
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Devil's claw
Natural anti-inflammatory that may reduce inflammatory pain. Also thought to interact with neurotransmitter systems.
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Cayenne/Capsaicin
Compound found in hot chili peppers that depletes substance P, a neurotransmitter involved in pain signaling.
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Valerian root
Herbal anxiolytic that may increase GABA, a neurotransmitter associated with reduced pain perception.
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St. John's Wort
Herb that may inhibit COMT activity similar to some pain medications. Also boosts serotonin which improves mood.
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Peppermint oil
Menthol is a COMT inhibitor. Peppermint oil applied topically may enhance painkilling dopamine effects.
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Boswellia
Anti-inflammatory herb that may disrupt cytokine signaling implicated in pain hypersensitivity.
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Cannabidiol (CBD)
Compound from cannabis that affects endocannabinoid receptors involved in pain processing.
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DLPA
Supplement containing amino acids that may prevent breakdown of endorphins for natural pain relief.
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5-HTP
Supplement that increases serotonin levels which may help with fibromyalgia and comorbid depression.
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Ginger
Contains anti-inflammatory gingerols that may inhibit pain-causing prostaglandins and leukotrienes.
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Arnica
Homeopathic pain remedy used topically that may reduce inflammation and impact serotonin.
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